The future of endoscopic treatment of early Barrett neoplasia: the endoscopist's view.

The field of Barrett’s esophagus ablation has come a long way since the original pioneering work of Brandt and Berenson in the early 1990s [1, 2]. In fact, ablation is now viewed as a legiti− mate first−line treatment option for healthy pa− tients with high grade dysplasia and early adeno− carcinoma, based on studies performed to date. Furthermore, the notion of complete ablation of Barrett’s esophagus has moved from concept to reality. That being said, many questions about endoscopic ablation of Barrett’s esophagus re− main unanswered. This section will try to address the following issues regarding the endoscopic ab− lation of Barrett’s esophagus: 1. Where have we been? 2. Where are we now? 3. What are currently unresolved issues in en− doscopic ablation? 4. What are potential solutions for these issues?